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ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration

Regenerative failure in the CNS largely depends on pronounced growth inhibitory signaling and reduced cellular survival after a lesion stimulus. One key mediator of growth inhibitory signaling is Rho-associated kinase (ROCK), which has been shown to modulate growth cone stability by regulation of ac...

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Detalhes bibliográficos
Main Authors: Tönges, Lars, Koch, Jan-Christoph, Bähr, Mathias, Lingor, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207219/
https://ncbi.nlm.nih.gov/pubmed/22065949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2011.00039
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