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Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease

Axonal degeneration is one of the earliest features of Parkinson’s disease pathology, which is followed by neuronal death in the substantia nigra and other parts of the brain. Inhibition of axonal degeneration combined with cellular neuroprotection therefore seem key to targeting an early stage in P...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tönges, Lars, Frank, Tobias, Tatenhorst, Lars, Saal, Kim A., Koch, Jan C., Szegő, Éva M., Bähr, Mathias, Weishaupt, Jochen H., Lingor, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501973/
https://ncbi.nlm.nih.gov/pubmed/23087045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws254
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