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Modulation of Microglial Activity by Rho-Kinase (ROCK) Inhibition as Therapeutic Strategy in Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Neurodegenerative diseases are characterized by the progressive degeneration of neurons in the central and peripheral nervous system (CNS, PNS), resulting in a reduced innervation of target structures and a loss of function. A shared characteristic of many neurodegenerative diseases is the infiltrat...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Roser, Anna-Elisa, Tönges, Lars, Lingor, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378706/
https://ncbi.nlm.nih.gov/pubmed/28420986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00094
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