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Modulation of Microglial Activity by Rho-Kinase (ROCK) Inhibition as Therapeutic Strategy in Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Neurodegenerative diseases are characterized by the progressive degeneration of neurons in the central and peripheral nervous system (CNS, PNS), resulting in a reduced innervation of target structures and a loss of function. A shared characteristic of many neurodegenerative diseases is the infiltrat...

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Détails bibliographiques
Publié dans:Front Aging Neurosci
Auteurs principaux: Roser, Anna-Elisa, Tönges, Lars, Lingor, Paul
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378706/
https://ncbi.nlm.nih.gov/pubmed/28420986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00094
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