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Modulation of Microglial Activity by Rho-Kinase (ROCK) Inhibition as Therapeutic Strategy in Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Neurodegenerative diseases are characterized by the progressive degeneration of neurons in the central and peripheral nervous system (CNS, PNS), resulting in a reduced innervation of target structures and a loss of function. A shared characteristic of many neurodegenerative diseases is the infiltrat...

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Опубликовано в: :Front Aging Neurosci
Главные авторы: Roser, Anna-Elisa, Tönges, Lars, Lingor, Paul
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378706/
https://ncbi.nlm.nih.gov/pubmed/28420986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00094
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