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Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration
Axonal degeneration is a key initiating event in many neurological diseases. Focal lesions to axons result in a rapid disintegration of the perilesional axon by acute axonal degeneration (AAD) within several hours. However, the underlying molecular mechanisms of AAD are only incompletely understood....
Sparad:
| I publikationen: | Sci Rep |
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| Huvudupphovsmän: | , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109185/ https://ncbi.nlm.nih.gov/pubmed/27845394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37050 |
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