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Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanthine oxidase activation

Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kovac, S, Domijan, A-M, Walker, M C, Abramov, A Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649505/
https://ncbi.nlm.nih.gov/pubmed/25275601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.390
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