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Nrf2 regulates ROS production by mitochondria and NADPH oxidase
BACKGROUND: Nuclear factor (erythroid-derived 2) factor 2 (Nrf2) is a crucial transcription factor mediating protection against oxidants. Nrf2 is negatively regulated by cytoplasmic Kelch-like ECH associated protein 1 (Keap1) thereby providing inducible antioxidant defence. Antioxidant properties of...
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| Publicado no: | Biochim Biophys Acta |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Pub. Co
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471129/ https://ncbi.nlm.nih.gov/pubmed/25484314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.11.021 |
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