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Silica particles cause NADPH oxidase–independent ROS generation and transient phagolysosomal leakage
Chronic inhalation of silica particles causes lung fibrosis and silicosis. Silica taken up by alveolar macrophages causes phagolysosomal membrane damage and leakage of lysosomal material into the cytoplasm to initiate apoptosis. We investigated the role of reactive oxygen species (ROS) in this membr...
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| Vydáno v: | Mol Biol Cell |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4569308/ https://ncbi.nlm.nih.gov/pubmed/26202463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-03-0126 |
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