Hydroxyurea-Increased Fetal Hemoglobin Is Associated with Less Organ Damage and Longer Survival in Adults with Sickle Cell Anemia

BACKGROUND: Adults with sickle cell anemia (HbSS) are inconsistently treated with hydroxyurea. OBJECTIVES: We retrospectively evaluated the effects of elevating fetal hemoglobin with hydroxyurea on organ damage and survival in patients enrolled in our screening study between 2001 and 2010. METHODS:...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Fitzhugh, Courtney D., Hsieh, Matthew M., Allen, Darlene, Coles, Wynona A., Seamon, Cassie, Ring, Michael, Zhao, Xiongce, Minniti, Caterina P., Rodgers, Griffin P., Schechter, Alan N., Tisdale, John F., Taylor, James G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648496/
https://ncbi.nlm.nih.gov/pubmed/26576059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141706
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