Hydroxyurea-Increased Fetal Hemoglobin Is Associated with Less Organ Damage and Longer Survival in Adults with Sickle Cell Anemia

BACKGROUND: Adults with sickle cell anemia (HbSS) are inconsistently treated with hydroxyurea. OBJECTIVES: We retrospectively evaluated the effects of elevating fetal hemoglobin with hydroxyurea on organ damage and survival in patients enrolled in our screening study between 2001 and 2010. METHODS:...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fitzhugh, Courtney D., Hsieh, Matthew M., Allen, Darlene, Coles, Wynona A., Seamon, Cassie, Ring, Michael, Zhao, Xiongce, Minniti, Caterina P., Rodgers, Griffin P., Schechter, Alan N., Tisdale, John F., Taylor, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648496/
https://ncbi.nlm.nih.gov/pubmed/26576059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141706
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