Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease

Hydroxyurea and higher hemoglobin F improve the clinical course and survival in sickle cell disease, but their roles in protecting from pulmonary hypertension are not clear. We studied 399 children and adolescents with sickle cell disease at steady state; 38% were being treated with hydroxyurea. Pat...

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Hauptverfasser: Gordeuk, Victor R., Campbell, Andrew, Rana, Sohail, Nouraie, Mehdi, Niu, Xiaomei, Minniti, Caterina P., Sable, Craig, Darbari, Deepika, Dham, Niti, Onyekwere, Onyinye, Ammosova, Tatiana, Nekhai, Sergei, Kato, Gregory J., Gladwin, Mark T., Castro, Oswaldo L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Clinical Trials and Observations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780300/
https://ncbi.nlm.nih.gov/pubmed/19724057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-218040
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