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Caspases shutdown nonsense-mediated mRNA decay during apoptosis

Nonsense-mediated mRNA decay (NMD) is an mRNA surveillance mechanism that plays integral roles in eliminating mRNAs with premature termination codons to prevent the synthesis of truncated proteins that could be pathogenic. One response to the accumulation of detrimental proteins is apoptosis, which...

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Publicat a:Cell Death Differ
Autors principals: Jia, J, Furlan, A, Gonzalez-Hilarion, S, Leroy, C, Gruenert, D C, Tulasne, D, Lejeune, F
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648321/
https://ncbi.nlm.nih.gov/pubmed/25744026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.18
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