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Caspases shutdown nonsense-mediated mRNA decay during apoptosis

Nonsense-mediated mRNA decay (NMD) is an mRNA surveillance mechanism that plays integral roles in eliminating mRNAs with premature termination codons to prevent the synthesis of truncated proteins that could be pathogenic. One response to the accumulation of detrimental proteins is apoptosis, which...

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Detalles Bibliográficos
Publicado en:Cell Death Differ
Main Authors: Jia, J, Furlan, A, Gonzalez-Hilarion, S, Leroy, C, Gruenert, D C, Tulasne, D, Lejeune, F
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648321/
https://ncbi.nlm.nih.gov/pubmed/25744026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.18
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