Caspases shutdown nonsense-mediated mRNA decay during apoptosis

Nonsense-mediated mRNA decay (NMD) is an mRNA surveillance mechanism that plays integral roles in eliminating mRNAs with premature termination codons to prevent the synthesis of truncated proteins that could be pathogenic. One response to the accumulation of detrimental proteins is apoptosis, which...

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Vydáno v:Cell Death Differ
Hlavní autoři: Jia, J, Furlan, A, Gonzalez-Hilarion, S, Leroy, C, Gruenert, D C, Tulasne, D, Lejeune, F
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648321/
https://ncbi.nlm.nih.gov/pubmed/25744026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.18
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