NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity

Multiple myeloma (MM) cells typically grow in focal lesions, stimulating osteoclasts that destroy bone and support MM. Osteoclasts and MM cells are hypermetabolic. The coenzyme nicotinamide adenine dinucleotide (NAD(+)) is not only essential for cellular metabolism; it also affects activity of NAD-d...

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Detaylı Bibliyografya
Yayımlandı:Exp Hematol
Asıl Yazarlar: Venkateshaiah, Sathisha Upparahalli, Khan, Sharmin, Ling, Wen, Bam, Rakesh, Li, Xin, van Rhee, Frits, Usmani, Saad, Barlogie, Bart, Epstein, Joshua, Yaccoby, Shmuel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648259/
https://ncbi.nlm.nih.gov/pubmed/23435312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.02.008
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