NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity

Multiple myeloma (MM) cells typically grow in focal lesions, stimulating osteoclasts that destroy bone and support MM. Osteoclasts and MM cells are hypermetabolic. The coenzyme nicotinamide adenine dinucleotide (NAD(+)) is not only essential for cellular metabolism; it also affects activity of NAD-d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Exp Hematol
Egile Nagusiak: Venkateshaiah, Sathisha Upparahalli, Khan, Sharmin, Ling, Wen, Bam, Rakesh, Li, Xin, van Rhee, Frits, Usmani, Saad, Barlogie, Bart, Epstein, Joshua, Yaccoby, Shmuel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648259/
https://ncbi.nlm.nih.gov/pubmed/23435312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.02.008
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