CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow

Hematopoietic stem cells (HSCs) depend on the bone marrow (BM) niche for their maintenance, proliferation, and differentiation. The BM niche is composed of nonhematopoietic and mature hematopoietic cells, including megakaryocytes (Mks). Thrombopoietin (Thpo) is a crucial cytokine produced by BM nich...

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Publicado en:J Exp Med
Autores principales: Nakamura-Ishizu, Ayako, Takubo, Keiyo, Kobayashi, Hiroshi, Suzuki-Inoue, Katsue, Suda, Toshio
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647260/
https://ncbi.nlm.nih.gov/pubmed/26552707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150057
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