CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow

Hematopoietic stem cells (HSCs) depend on the bone marrow (BM) niche for their maintenance, proliferation, and differentiation. The BM niche is composed of nonhematopoietic and mature hematopoietic cells, including megakaryocytes (Mks). Thrombopoietin (Thpo) is a crucial cytokine produced by BM nich...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Nakamura-Ishizu, Ayako, Takubo, Keiyo, Kobayashi, Hiroshi, Suzuki-Inoue, Katsue, Suda, Toshio
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2015
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647260/
https://ncbi.nlm.nih.gov/pubmed/26552707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150057
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