CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow

Hematopoietic stem cells (HSCs) depend on the bone marrow (BM) niche for their maintenance, proliferation, and differentiation. The BM niche is composed of nonhematopoietic and mature hematopoietic cells, including megakaryocytes (Mks). Thrombopoietin (Thpo) is a crucial cytokine produced by BM nich...

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Nakamura-Ishizu, Ayako, Takubo, Keiyo, Kobayashi, Hiroshi, Suzuki-Inoue, Katsue, Suda, Toshio
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647260/
https://ncbi.nlm.nih.gov/pubmed/26552707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150057
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