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CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow

Hematopoietic stem cells (HSCs) depend on the bone marrow (BM) niche for their maintenance, proliferation, and differentiation. The BM niche is composed of nonhematopoietic and mature hematopoietic cells, including megakaryocytes (Mks). Thrombopoietin (Thpo) is a crucial cytokine produced by BM nich...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Nakamura-Ishizu, Ayako, Takubo, Keiyo, Kobayashi, Hiroshi, Suzuki-Inoue, Katsue, Suda, Toshio
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647260/
https://ncbi.nlm.nih.gov/pubmed/26552707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150057
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