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CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow

Hematopoietic stem cells (HSCs) depend on the bone marrow (BM) niche for their maintenance, proliferation, and differentiation. The BM niche is composed of nonhematopoietic and mature hematopoietic cells, including megakaryocytes (Mks). Thrombopoietin (Thpo) is a crucial cytokine produced by BM nich...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Nakamura-Ishizu, Ayako, Takubo, Keiyo, Kobayashi, Hiroshi, Suzuki-Inoue, Katsue, Suda, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647260/
https://ncbi.nlm.nih.gov/pubmed/26552707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150057
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