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The Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological Ligand
Increased ligand binding to integrin (“activation”) underpins many biological processes, such as leukocyte trafficking, cell migration, host-pathogen interaction, and hemostasis. Integrins exist in several conformations, ranging from compact and bent to extended and open. However, the exact conforma...
Uloženo v:
| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646401/ https://ncbi.nlm.nih.gov/pubmed/26391523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682377 |
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