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Full-length membrane bound TNF alpha acts through TNF receptor 2 to modify the phenotype of sensory neurons

Neuropathic pain resulting from spinal hemisection or selective spinal nerve ligation is characterized by an increase in membrane-bound TNF alpha (mTNFα) in spinal microglia without detectable release of soluble TNF alpha (sTNFα). In tissue culture, we showed that full length transmembrane cleavage-...

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Main Authors: Wu, Zetang, Wang, Shiyong, Gruber, Sandy, Mata, Marina, Fink, David J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748157/
https://ncbi.nlm.nih.gov/pubmed/23711481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.05.038
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