Coarse-Grained Simulation of Full-Length Integrin Activation

Integrin conformational dynamics are critical to their receptor and signaling functions in many cellular processes, including spreading, adhesion, and migration. However, assessing integrin conformations is both experimentally and computationally challenging because of limitations in resolution and...

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Vydáno v:Biophys J
Hlavní autoři: Bidone, Tamara C., Polley, Anirban, Jin, Jaehyeok, Driscoll, Tristan, Iwamoto, Daniel V., Calderwood, David A., Schwartz, Martin A., Voth, Gregory A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428961/
https://ncbi.nlm.nih.gov/pubmed/30851876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.02.011
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