Coarse-Grained Simulation of Full-Length Integrin Activation

Integrin conformational dynamics are critical to their receptor and signaling functions in many cellular processes, including spreading, adhesion, and migration. However, assessing integrin conformations is both experimentally and computationally challenging because of limitations in resolution and...

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Bibliographic Details
Published in:Biophys J
Main Authors: Bidone, Tamara C., Polley, Anirban, Jin, Jaehyeok, Driscoll, Tristan, Iwamoto, Daniel V., Calderwood, David A., Schwartz, Martin A., Voth, Gregory A.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2019
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428961/
https://ncbi.nlm.nih.gov/pubmed/30851876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.02.011
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