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The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E

The triggering receptor expressed on myeloid cells 2 (TREM2) is an Ig-like V-type receptor expressed by populations of myeloid cells in the central nervous system and periphery. Loss-of-function mutations in TREM2 cause a progressive, fatal neurodegenerative disorder called Nasu-Hakola disease. In a...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Bailey, Charles C., DeVaux, Lindsey B., Farzan, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646256/
https://ncbi.nlm.nih.gov/pubmed/26374897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677286
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