Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2

Endoplasmic reticulum (ER) aminopeptidases process antigenic peptide precursors to generate epitopes for presentation by MHC class I molecules and help shape the antigenic peptide repertoire and cytotoxic T-cell responses. To perform this function, ER aminopeptidases have to recognize and process a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mpakali, Anastasia, Giastas, Petros, Mathioudakis, Nikolas, Mavridis, Irene M., Saridakis, Emmanuel, Stratikos, Efstratios
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646255/
https://ncbi.nlm.nih.gov/pubmed/26381406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.685909
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