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Molecular pathways for antigenic peptide generation by ER aminopeptidase 1
Endoplasmic Reticulum aminopeptidase 1 (ERAP1) is an intracellular enzyme that can generate or destroy potential peptide ligands for MHC class I molecules. ERAP1 activity influences the cell-surface immunopeptidome and epitope immunodominance patterns but in complex and poorly understood manners. Tw...
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| Publicado no: | Mol Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192871/ https://ncbi.nlm.nih.gov/pubmed/29678301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2018.03.026 |
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