Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway

The insulin/insulin-like growth factor (IGF)-1 signaling pathway (ISP) plays a fundamental role in long term health in a range of organisms. Protein kinases including Akt and ERK are intimately involved in the ISP. To identify other kinases that may participate in this pathway or intersect with it i...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Trefely, Sophie, Khoo, Poh-Sim, Krycer, James R., Chaudhuri, Rima, Fazakerley, Daniel J., Parker, Benjamin L., Sultani, Ghazal, Lee, James, Stephan, Jean-Philippe, Torres, Eric, Jung, Kenneth, Kuijl, Coenraad, James, David E., Junutula, Jagath R., Stöckli, Jacqueline
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646237/
https://ncbi.nlm.nih.gov/pubmed/26342081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.658815
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