Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes

Insulin signaling augments glucose transport by regulating glucose transporter 4 (GLUT4) trafficking from specialized intracellular compartments, termed GLUT4 storage vesicles (GSVs), to the plasma membrane. Proteomic analysis of GSVs by mass spectrometry revealed enrichment of 59 proteins in these...

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發表在:J Biol Chem
Main Authors: Fazakerley, Daniel J., Naghiloo, Sheyda, Chaudhuri, Rima, Koumanov, Françoise, Burchfield, James G., Thomas, Kristen C., Krycer, James R., Prior, Matthew J., Parker, Ben L., Murrow, Beverley A., Stöckli, Jacqueline, Meoli, Christopher C., Holman, Geoffrey D., James, David E.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2015
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583025/
https://ncbi.nlm.nih.gov/pubmed/26240143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657361
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