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Insulin regulates Rab3–Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes

AIMS/HYPOTHESIS: The glucose transporter GLUT4 is present mainly in insulin-responsive tissues of fat, heart and skeletal muscle and is translocated from intracellular membrane compartments to the plasma membrane (PM) upon insulin stimulation. The transit of GLUT4 to the PM is known to be dependent...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Koumanov, Francoise, Pereira, Vinit J., Richardson, Judith D., Sargent, Samantha L., Fazakerley, Daniel J., Holman, Geoffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499112/
https://ncbi.nlm.nih.gov/pubmed/26024738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3627-3
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