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Insulin regulates Rab3–Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes

AIMS/HYPOTHESIS: The glucose transporter GLUT4 is present mainly in insulin-responsive tissues of fat, heart and skeletal muscle and is translocated from intracellular membrane compartments to the plasma membrane (PM) upon insulin stimulation. The transit of GLUT4 to the PM is known to be dependent...

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Publicat a:Diabetologia
Autors principals: Koumanov, Francoise, Pereira, Vinit J., Richardson, Judith D., Sargent, Samantha L., Fazakerley, Daniel J., Holman, Geoffrey D.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499112/
https://ncbi.nlm.nih.gov/pubmed/26024738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3627-3
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