Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity

OBJECTIVE: Insulin resistance (IR) is one of the earliest predictors of type 2 diabetes. However, diagnosis of IR is limited. High fat fed mouse models provide key insights into IR. We hypothesized that early features of IR are associated with persistent changes in gene expression (GE) and endeavore...

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Udgivet i:NPJ Syst Biol Appl
Main Authors: Chaudhuri, Rima, Khoo, Poh Sim, Tonks, Katherine, Junutula, Jagath R, Kolumam, Ganesh, Modrusan, Zora, Samocha-Bonet, Dorit, Meoli, Christopher C, Hocking, Samantha, Fazakerley, Daniel J, Stöckli, Jacqueline, Hoehn, Kyle L, Greenfield, Jerry R, Yang, Jean Yee Hwa, James, David E
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516867/
https://ncbi.nlm.nih.gov/pubmed/28725461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjsba.2015.10
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