Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson’s disease

There are no cures for neurodegenerative diseases and this is partially due to the difficulty of monitoring pathogenic molecules in patients during life. The Parkinson’s disease gene α-synuclein (SNCA) is selectively expressed in blood cells and neurons. Here we show that SNCA transcripts in circula...

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Publicado en:Brain
Main Authors: Locascio, Joseph J., Eberly, Shirley, Liao, Zhixiang, Liu, Ganqiang, Hoesing, Ashley N., Duong, Karen, Trisini-Lipsanopoulos, Ana, Dhima, Kaltra, Hung, Albert Y., Flaherty, Alice W., Schwarzschild, Michael A., Hayes, Michael T., Wills, Anne-Marie, Shivraj Sohur, U., Mejia, Nicte I., Selkoe, Dennis J., Oakes, David, Shoulson, Ira, Dong, Xianjun, Marek, Ken, Zheng, Bin, Ivinson, Adrian, Hyman, Bradley T., Growdon, John H., Sudarsky, Lewis R., Schlossmacher, Michael G., Ravina, Bernard, Scherzer, Clemens R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643625/
https://ncbi.nlm.nih.gov/pubmed/26220939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv202
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