Association of SNCA with Parkinson: replication in the Harvard NeuroDiscovery Center Biomarker Study

BACKGROUND: Mutations in the α-synuclein gene (SNCA) cause autosomal dominant forms of Parkinson’s disease, but the substantial risk conferred by this locus to the common sporadic disease has only recently emerged from genome-wide association studies. METHODS: Here we genotyped a prioritized non-cod...

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Main Authors: Ding, Hongliu, Sarokhan, Alison K., Roderick, Sarah S., Bakshi, Rachit, Maher, Nancy E., Ashourian, Paymon, Kan, Caroline G., Chang, Sunny, Santarlasci, Andrea, Swords, Kyleen E., Ravina, Bernard M., Hayes, Michael T., Sohur, U. Shivraj, Wills, Anne-Marie, Flaherty, Alice W., Unni, Vivek K., Hung, Albert Y., Selkoe, Dennis J., Schwarzschild, Michael A., Schlossmacher, Michael G., Sudarsky, Lewis R., Growdon, John H., Ivinson, Adrian J., Hyman, Bradley T., Scherzer, Clemens R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337217/
https://ncbi.nlm.nih.gov/pubmed/21953863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.23934
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