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Hydrogen peroxide-activatable antioxidant prodrug as a targeted therapeutic agent for ischemia-reperfusion injury
Overproduction of hydrogen peroxide (H(2)O(2)) causes oxidative stress and is the main culprit in the pathogenesis of ischemia/reperfusion (I/R) injury. Suppression of oxidative stress is therefore critical in the treatment of I/R injury. Here, we report H(2)O(2)-activatable antioxidant prodrug (BRA...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643254/ https://ncbi.nlm.nih.gov/pubmed/26563741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16592 |
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