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Mitochondria to nucleus translocation of AIF in mice lacking Hsp70 during ischemia/reperfusion

Heat shock protein 70 (Hsp70) has been shown to have an anti-apoptotic function, but its mechanism is not clear in heart. In this study, we examined the effect of Hsp70 deletion on AIF-induced apoptosis during ischemia/reperfusion (I/R) in vivo. Although Hsp70 KO and WT mice demonstrated similar amo...

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Detalhes bibliográficos
Main Authors: Choudhury, Sangita, Bae, Soochan, Ke, Qingen, Lee, Ji Yoo, Kim, Jacob, Kang, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205442/
https://ncbi.nlm.nih.gov/pubmed/21387140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-011-0164-1
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