Hydrogen peroxide-responsive copolyoxalate nanoparticles for detection and therapy of ischemia–reperfusion injury

The main culprit in the pathogenesis of ischemia/reperfusion (I/R) injury is the generation of high level of hydrogen peroxide (H(2)O(2)). In this study, we report a novel diagnostic and therapeutic strategy for I/R injury based on H(2)O(2)-activatable copolyoxalate nanoparticles using a murine mode...

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Publicado no:J Control Release
Main Authors: Lee, Dongwon, Bae, Soochan, Ke, Qingen, Lee, Jiyoo, Song, Byungjoo, Karumanchi, S. Ananth, Khang, Gilson, Choi, Hak Soo, Kang, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389767/
https://ncbi.nlm.nih.gov/pubmed/24096013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.09.020
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