H(2)O(2)-responsive molecularly engineered polymer nanoparticles as ischemia/reperfusion-targeted nanotherapeutic agents

The main culprit in the pathogenesis of ischemia/reperfusion (I/R) injury is the overproduction of reactive oxygen species (ROS). Hydrogen peroxide (H(2)O(2)), the most abundant form of ROS produced during I/R, causes inflammation, apoptosis and subsequent tissue damages. Here, we report H(2)O(2)-re...

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Bibliografiske detaljer
Main Authors: Lee, Dongwon, Bae, Soochan, Hong, Donghyun, Lim, Hyungsuk, Yoon, Joo Heung, Hwang, On, Park, Seunggyu, Ke, Qingen, Khang, Gilson, Kang, Peter M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715762/
https://ncbi.nlm.nih.gov/pubmed/23868607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02233
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