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Versatile Strategy for the Divergent Synthesis of Linear Oligosaccharide Domain Variants of Quillaja Saponin Vaccine Adjuvants

We describe a new, versatile synthetic approach to Quillaja saponin variants based on the natural product immunoadjuvant QS-21. This modular, divergent strategy provides efficient access to linear oligosaccharide domain variants with modified sugars and regiochemistries. This new synthetic approach...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Commun (Camb)
Main Authors: Fernández-Tejada, Alberto, Tan, Derek S., Gin, David Y.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643164/
https://ncbi.nlm.nih.gov/pubmed/26243268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc05244k
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