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AIF inhibits tumor metastasis by protecting PTEN from oxidation

Apoptosis-inducing factor (AIF) exerts dual roles on cell death and survival, but its substrates as a putative oxidoreductase and roles in tumorigenesis remain elusive. Here, we report that AIF physically interacts with and inhibits the oxidation of phosphatase and tensin homolog on chromosome ten (...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO Rep
Päätekijät: Shen, Shao-Ming, Guo, Meng, Xiong, Zhong, Yu, Yun, Zhao, Xu-Yun, Zhang, Fei-Fei, Chen, Guo-Qiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley & Sons, Ltd 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641507/
https://ncbi.nlm.nih.gov/pubmed/26415504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540536
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