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Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress
Delayed neuronal cell death largely contributes to the progressive infarct development and associated functional impairments after cerebral ischemia or brain trauma. Previous studies exposed a key role for the interaction of the mitochondrial protein apoptosis-inducing factor (AIF) and cytosolic cyc...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040673/ https://ncbi.nlm.nih.gov/pubmed/24434516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.518 |
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