Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress

Delayed neuronal cell death largely contributes to the progressive infarct development and associated functional impairments after cerebral ischemia or brain trauma. Previous studies exposed a key role for the interaction of the mitochondrial protein apoptosis-inducing factor (AIF) and cytosolic cyc...

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Bibliographic Details
Main Authors:	Doti, N, Reuther, C, Scognamiglio, P L, Dolga, A M, Plesnila, N, Ruvo, M, Culmsee, C
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2014
Subjects:	Original Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4040673/ https://ncbi.nlm.nih.gov/pubmed/24434516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.518
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Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress

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