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Activation of SK2 channels preserves ER Ca(2+) homeostasis and protects against ER stress-induced cell death

Alteration of endoplasmic reticulum (ER) Ca(2+) homeostasis leads to excessive cytosolic Ca(2+) accumulation and delayed neuronal cell death in acute and chronic neurodegenerative disorders. While our recent studies established a protective role for SK channels against excessive intracellular Ca(2+)...

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Podrobná bibliografie
Vydáno v:Cell Death Differ
Hlavní autoři: Richter, M, Vidovic, N, Honrath, B, Mahavadi, P, Dodel, R, Dolga, A M, Culmsee, C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832102/
https://ncbi.nlm.nih.gov/pubmed/26586570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.146
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