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SK channel activation is neuroprotective in conditions of enhanced ER–mitochondrial coupling

Alterations in the strength and interface area of contact sites between the endoplasmic reticulum (ER) and mitochondria contribute to calcium (Ca(2+)) dysregulation and neuronal cell death, and have been implicated in the pathology of several neurodegenerative diseases. Weakening this physical linka...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Honrath, Birgit, Krabbendam, Inge E., IJsebaart, Carmen, Pegoretti, Valentina, Bendridi, Nadia, Rieusset, Jennifer, Schmidt, Martina, Culmsee, Carsten, Dolga, Amalia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964177/
https://ncbi.nlm.nih.gov/pubmed/29789578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0590-1
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