SK channel activation is neuroprotective in conditions of enhanced ER–mitochondrial coupling

Alterations in the strength and interface area of contact sites between the endoplasmic reticulum (ER) and mitochondria contribute to calcium (Ca(2+)) dysregulation and neuronal cell death, and have been implicated in the pathology of several neurodegenerative diseases. Weakening this physical linka...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Honrath, Birgit, Krabbendam, Inge E., IJsebaart, Carmen, Pegoretti, Valentina, Bendridi, Nadia, Rieusset, Jennifer, Schmidt, Martina, Culmsee, Carsten, Dolga, Amalia M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964177/
https://ncbi.nlm.nih.gov/pubmed/29789578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0590-1
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