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Activation of KCNN3/SK3/K(Ca)2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia

In neurons, small-conductance calcium activated potassium (KCNN/SK/K(Ca)2) channels maintain calcium homeostasis after NMDA receptor activation, thereby preventing excitotoxic neuronal death. So far, little is known about the function of KCNN/SK/K(Ca)2 channels in non-neuronal cells, such as microgl...

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Detalhes bibliográficos
Main Authors: Dolga, Amalia M., Letsche, Till, Gold, Maike, Doti, Nunzianna, Bacher, Michael, Chiamvimonvat, Nipavan, Dodel, Richard, Culmsee, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799773/
https://ncbi.nlm.nih.gov/pubmed/23002008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22419
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