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Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress

Delayed neuronal cell death largely contributes to the progressive infarct development and associated functional impairments after cerebral ischemia or brain trauma. Previous studies exposed a key role for the interaction of the mitochondrial protein apoptosis-inducing factor (AIF) and cytosolic cyc...

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Библиографические подробности
Главные авторы: Doti, N, Reuther, C, Scognamiglio, P L, Dolga, A M, Plesnila, N, Ruvo, M, Culmsee, C
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040673/
https://ncbi.nlm.nih.gov/pubmed/24434516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.518
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