Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress

Reactive oxygen species (ROS) are key regulators in cell proliferation, survival, tumor initiation and development. However, the role of ROS in tumor metastasis is less clear. Here, we show that oxidative stress inhibited tumor metastasis via activation of Hippo kinase MST1/2, which led to the phosp...

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Publicat a:Redox Biol
Autors principals: Wang, Yang, Li, Juan, Gao, Ya, Luo, Yue, Luo, Hong, Wang, Liang, Yi, Yong, Yuan, Zengqiang, Jim Xiao, Zhi-Xiong
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582208/
https://ncbi.nlm.nih.gov/pubmed/31212215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101233
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