Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress

Reactive oxygen species (ROS) are key regulators in cell proliferation, survival, tumor initiation and development. However, the role of ROS in tumor metastasis is less clear. Here, we show that oxidative stress inhibited tumor metastasis via activation of Hippo kinase MST1/2, which led to the phosp...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Wang, Yang, Li, Juan, Gao, Ya, Luo, Yue, Luo, Hong, Wang, Liang, Yi, Yong, Yuan, Zengqiang, Jim Xiao, Zhi-Xiong
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582208/
https://ncbi.nlm.nih.gov/pubmed/31212215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101233
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