Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress

Reactive oxygen species (ROS) are key regulators in cell proliferation, survival, tumor initiation and development. However, the role of ROS in tumor metastasis is less clear. Here, we show that oxidative stress inhibited tumor metastasis via activation of Hippo kinase MST1/2, which led to the phosp...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Wang, Yang, Li, Juan, Gao, Ya, Luo, Yue, Luo, Hong, Wang, Liang, Yi, Yong, Yuan, Zengqiang, Jim Xiao, Zhi-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582208/
https://ncbi.nlm.nih.gov/pubmed/31212215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101233
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