TET1 inhibits gastric cancer growth and metastasis by PTEN demethylation and re-expression

Ten-Eleven Translocation 1 (TET1) is a member of ten eleven translocation enzymes, which convert 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC). TET1 can promote CpG islands demethylation in specific genes and often absent in various cancers. Herein, we found that TET1 expression and 5-h...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Pei, Yao-fei, Tao, Ran, Li, Jian-fang, Su, Li-ping, Yu, Bei-qin, Wu, Xiong-yan, Yan, Min, Gu, Qin-long, Zhu, Zheng-gang, Liu, Bing-ya
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058759/
https://ncbi.nlm.nih.gov/pubmed/27121319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8900
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