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AIF inhibits tumor metastasis by protecting PTEN from oxidation

Apoptosis-inducing factor (AIF) exerts dual roles on cell death and survival, but its substrates as a putative oxidoreductase and roles in tumorigenesis remain elusive. Here, we report that AIF physically interacts with and inhibits the oxidation of phosphatase and tensin homolog on chromosome ten (...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Shen, Shao-Ming, Guo, Meng, Xiong, Zhong, Yu, Yun, Zhao, Xu-Yun, Zhang, Fei-Fei, Chen, Guo-Qiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Ltd 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641507/
https://ncbi.nlm.nih.gov/pubmed/26415504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540536
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