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An Evolutionarily Conserved Autoinhibitory Molecular Switch in ELMO Proteins Regulates Rac Signaling
Dedicator of cytokinesis (DOCK) proteins are guanine nucleotide exchange factors (GEFs) controlling the activity of Rac1/Cdc42 during migration, phagocytosis, and myoblast fusion [1–4]. Engulfment and cell motility (ELMO) proteins bind a subset of DOCK members and are emerging as critical regulators...
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| 出版年: | Curr Biol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640902/ https://ncbi.nlm.nih.gov/pubmed/21035343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.10.028 |
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