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The Arf Family GTPase Arl4A Complexes with ELMO Proteins to Promote Actin Cytoskeleton Remodeling and Reveals a Versatile Ras-binding Domain in the ELMO Proteins Family

The prototypical DOCK protein, DOCK180, is an evolutionarily conserved Rac regulator and is indispensable during processes such as cell migration and myoblast fusion. The biological activity of DOCK180 is tightly linked to its binding partner ELMO. We previously reported that autoinhibited ELMO prot...

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Bibliographische Detailangaben
Hauptverfasser: Patel, Manishha, Chiang, Tsai-Chen, Tran, Viviane, Lee, Fang-Jen S., Côté, Jean-François
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234722/
https://ncbi.nlm.nih.gov/pubmed/21930703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.274191
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