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The Arf Family GTPase Arl4A Complexes with ELMO Proteins to Promote Actin Cytoskeleton Remodeling and Reveals a Versatile Ras-binding Domain in the ELMO Proteins Family

The prototypical DOCK protein, DOCK180, is an evolutionarily conserved Rac regulator and is indispensable during processes such as cell migration and myoblast fusion. The biological activity of DOCK180 is tightly linked to its binding partner ELMO. We previously reported that autoinhibited ELMO prot...

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Detalhes bibliográficos
Main Authors: Patel, Manishha, Chiang, Tsai-Chen, Tran, Viviane, Lee, Fang-Jen S., Côté, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234722/
https://ncbi.nlm.nih.gov/pubmed/21930703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.274191
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