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ELMO Recruits Actin Cross-linking Family 7 (ACF7) at the Cell Membrane for Microtubule Capture and Stabilization of Cellular Protrusions

ELMO and DOCK180 proteins form an evolutionarily conserved module controlling Rac GTPase signaling during cell migration, phagocytosis, and myoblast fusion. Here, we identified the microtubule and actin-binding spectraplakin ACF7 as a novel ELMO-interacting partner. A C-terminal polyproline segment...

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Detalhes bibliográficos
Main Authors: Margaron, Yoran, Fradet, Nadine, Côté, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543002/
https://ncbi.nlm.nih.gov/pubmed/23184944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.431825
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