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From residue coevolution to protein conformational ensembles and functional dynamics
The analysis of evolutionary amino acid correlations has recently attracted a surge of renewed interest, also due to their successful use in de novo protein native structure prediction. However, many aspects of protein function, such as substrate binding and product release in enzymatic activity, ca...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640757/ https://ncbi.nlm.nih.gov/pubmed/26487681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508584112 |
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